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Dolovent™ is safe to use and there are no serious side effects that have been reported or seen during studies. The changes you might notice are that riboflavin (Vitamin B2) may cause urine to turn bright yellow and some people experience mild bloating and loose stools due to the increased amounts of magnesium. Dolovent™ is manufactured to the highest standards of quality and purity. It should not, however, be used with other products that contain magnesium or vitamin B2.

Dolovent™ has not been shown to cause any adverse drug interactions and can be taken safely along with prescription medications (e.g. triptans and beta blockers). However, to optimise absorption of Dolovent™ and to ensure the absorption of certain medications isn’t affected, Dolovent™ should be taken two hours away from drugs with the following active ingredients: tetracyclines, ferrous-containing substances, sodium fluoride, isoniazid, chlorpromazine and digoxin. 

If you are worried about Dolovent™ and interaction with your medication, consult your health practitioner or GP.

Dolovent™ is an over the counter (OTC) food supplement which means you can purchase it without a prescription from your GP. However, it is always a good idea to check with your doctor when you begin taking any supplement. You can simply purchase Dolovent™ from our store page or visit your local health food store or pharmacy if they stock Dolovent™.

Dolovent™ should be used with a distance of 1 – 2 hours if you are taking drugs containing the following active ingredients: Tetracyclines, ferrous-containing substances, Sodium fluoride, isoniazid, chlorpromazine and digoxin.

Take 2 Dolovent™ capsules twice daily with or after a meal – once in the morning and once in the evening.

Though normal levels of magnesium, B2 and CoQ10 may be restored in as little as a week, clinical evidence has shown that Dolovent™ is most effective when taken regularly over at least three months. This is sufficient time to allow all key ingredients in Dolovent™ to exert their full effect in the body.

Dolovent™ capsules contain a specific combination of the key ingredients magnesium (600mg) and riboflavin (400mg) which have been clinically proven and shown to contribute to the normal functioning of the nervous system, a reduction of tiredness and fatigue and further contributes to normal psychological function. Dolovent also contains co-enzyme Q10 (150mg) as well as further vitamins and minerals,

The ingredients in Dolovent™ are shown in the table below.

Nutritional ValuePer daily serving (4 capsules)% NRV*
Vitamin A (RE**)750 µg94%
Vitamin C200 mg250%
Vitamin E (alpha-TE***)134 mg1117%
Thiamine5.0 mg455%
Riboflavin400 mg28571%
Niacin (NE****)20 mg125%
Vitamin B65.0 mg357%
Vitamin B126.0 µg240%
Folic Acid400 µg200%
Vitamin D5.0 µg100%
Pantothenic Acid10 mg167%
Biotin165 µg330%
Iron0.8 mg6%
Zinc5.0 mg50%
Manganese2 mg100%
Copper500 µg50%
Chromium30 µg75%
Molybdenum60 µg120%
Selenium50 µg91%
Coenzyme Q10150 mg
Bioflavonoids5.0 mg

* Nutrient Reference Value, according to regulation (EU) No 1169/2011

** RE Retinol equivalents

*** TE Tocepherol equivalents

**** NE Niacine equivalents


We with our partners at Sun Genomics truly believe in the value of re-testing over a period of time for you to really understand the changes and improvements to your microbiome. In doing so this also allows us to reformulate as your microbiome changes, and allows you to improve and be at your gut best.

When the subscription renews about halfway through your first supply of your personalised formulation, a new sampling kit will be shipped out to you. The sooner you return it, the sooner we can show you how your gut has improved and get the new formulation shipped out to you.

Your microbiome is always subject to change: if you take antibiotics, have a severe illness, or even change your diet, your gut microbiome will change. We provide you with a personalised microbiome supplement that will last for three months and you can renew your subscription to re-test and reformulate, accommodating for any changes to your microbiome.

Floré uses the next generation of microbiome analysis allowing us to extract and gain a deeper insight of your gut composition, recording which microbes your body has both lack and ample supply of. Our patented analysis process, allows us to carefully select and craft a personalised microbiome supplement that is designed specifically for your gut needs.

Floré is blended together with the best pre and pro live bacteria, mixed with botanical ingredients from our growing repository of 100+ live bacteria to create you, your truly tailored formula. Your personalised formula is made using only the highest quality bacterial strains, tested and proven to reach your gut and provide an optimum dose of live bacteria for your diet and lifestyle.

Floré is the only one that uses Whole Genome Sequencing (WGS) as it consistently provides the most robust and in-depth level of data, including interpretation of individual microbes and uncovering strain level variances between organisms.

We have run rigorous testing in house to understand the viability of the strains in each of our live bacteria under specific temperature conditions and have shown that your personalised formula will not be impacted by temperature change. Most bacteria strains can endure temperatures of up to 44 °C and all are happy and active at a body temperature of 36°C.  

Your personalised microbiome supplement is cold shipped to ensure survivability and the bamboo travel jar included in your purpose protects the live bacteria for up to 30 days at room temperature.

It currently takes between 4-6 weeks from the day we receive your sample to the day we ship your formulation. You will however receive your Microbiome Analysis Report in the online customer portal normally within 7 days from receiving your sample.

The renewal rate is the same low price of £399 with free shipping and returns. You will receive the test kit and another newly formulated batch of 3 months’ supply of your personalised microbiome supplement.

Our customers may also opt to purchase the same microbiome formula without a retest for £299 with free shipping for another 3 month supply. Just email the Nouveau Healthcare team: with your kit ID and customer name and we will get your personalised microbiome supplement shipped out within 4 weeks.

Your Floré purchase includes 1 microbiome test as well as three months of your personalised formulation of microbiome supplements.

Not at all. Sun Genomics tested a large number of people and the results showed that there were significant microbiome shifts in only 3 weeks of taking the Floré personalised microbiome supplement.

Floré includes a microbiome collection kit which will be used to collect your stool sample, your online digital gut health analysis report and three months’ worth of your personalised microbiome supplement. All the shipping and delivery is included in the price.

If you subscribe to Floré there is an automatic renewal option, wherein after your first 90 day supply of your personalised microbiome supplements has ended we will send you out a new microbiome collection kit so you can provide us with a new stool sample. Once retested, we will update your online portal with your new report and provide you with a new set of your personalised microbiome supplement allowing you to track your gut health journey and adapt your supplement to your gut needs.

You may have seen the words “microbiome” and “microflora” when we mention Floré, but you may be wondering what do those words actually mean? The microbiome is the DNA of all the microflora in your gut. The microflora (sometimes also referred to as microbiota) is all the actual cells of bacteria, fungi, viruses, etc. that live in your gut. Imagine your gut is a garden filled with all of these beneficial vegetables and unfavourable weeds. You want to make sure you’re feeding your good vegetables all the nutrients they need and decreasing the number of weeds in your garden. Custom personalised microbiome supplements provides you with all the soil (natural botanicals like tumeric), seeds (unique live pre and pro bacteria strains), and fertilizer (specialised fibres and oligosaccharides) so your garden can flourish. Floré is designed to support your microbiome and microflora to flourish.

You may order a 3-month refill of your initial personalised formulation for £299 with free shipping. Please contact us directly: to place the order as they are not available to be purchased off of the website.

Your Floré gut journey includes an easy-to-use at-home microbiome collection kit, an in-depth digital microbiome analysis report and most importantly your lab-crafted personalised microbiome supplement manufactured in our partners Sun Genomics GMP facility in San Diego, California.

Your Floré supplement formula contains: 90 capsules, 90 day supply of your tailored formula.

The microbiome is the collection of all the microbes and their corresponding set of genes. The microbiologists at Sun Genomics focus on the microbiome located in the gut. A common misconception is that all these microbes are bad for you, but that is not true; microbes play an integral role in aiding the body’s immunological, nutritional, and metabolic functions.

Using whole genome sequencing (WGS), we are able to detect any microbe as well as its relative abundance. This includes bacteria, viruses, yeast, fungus, archaea, and parasites.

It’s important to note that every person is different in both their gut profile as well as their reaction to supplements and live bacteria. Therefore, everyone’s results and reaction time is a variable that we cannot predict. However, with our interactive portal and Whole Genome Sequencing (WGS) gut test kit we can track the improvement and change in your gut bacteria and watch your health score improve.

Our Sun Genomics team use cutting edge sequencing technology to analyse your gut microbiome and micro-manufacture each live bacteria supplement to ensure quality, sustainability and most of all a truly personalised supplement to improve your gut health. Good science and personalisation takes some time as every piece is reviewed by the Sun Genomics team of scientists. Currently, customers should expect to receive their personalised formula within 4-6 weeks after their test.

Everything we do is in-house. The sequencing of your sample and the formulation of your personalised microbiome supplement is done from the Sun Genomics head quarters in San Diego, California. The fulfilment of your test kit, personalised microbiome supplement and all support is taken up by your dedicated Nouveau Healthcare team.

Everyone is different in how they plan to manage their microbiome. As your microbiome improves and diversifies your personalised microbiome supplement of Floré changes too, all tracked simply from your portal and with your gut test. After three months we encourage all our customers to retest and see how their microbiome has changed.

L. reuteri DSM 17648

L. Reuteri DSM 17648 has a long history of safe use within the food chain. Lactobacillus reuteri is included in the European Food Safety Associations (EFSA) list of microorganisms for Qualified Presumption of Safety (QPS). QPS status implies that the specific strain has not been associated with safety issues. It can therefore be safely consumed by adults and children from 4 years and above.

L. Reuteri DSM 17648 exhibits glycoproteins on its surface which recognise and bind to glycoproteins exhibited from specific bacteria that reside in the stomach. These structures are unique to this strain of L. reuteri.

Other strains of L. reuteri and probiotics are usually intended to reach the gut where they can multiply and colonise in order to promote healthy gut bacteria. However, L. Reuteri DSM 17648 is an inactivated (i.e. dead) strain of L. reuteri which is not intended to colonise in the gut. Instead, it is intended to bind to specific gut bacteria, after which, L. Reuteri DSM 17648 and the gut bacteria bound to it will travel through the digestive tract where they will be eliminated through natural bowel movements.

Once the bacterium is bound to by L. Reuteri DSM 17648, it simply travels through the gastrointestinal tract and passes out via natural bowel movement.

L. Reuteri DSM 17648 contains a patented strain of Lactobacillus reuteri (DSM 17648) which, in studies, has shown to specifically binds and co-aggregate to specific bacteria that resides in the stomach. Thanks to this unique mode of action this has allowed L. Reuteri DSM 17648 to give the body a natural way of fighting the bacteria, supporting a healthy stomach environment and good gastric function.


Toxaprevent is designed for daily use and can be taken on a continuous basis. Reports have shown that long term use (10+ years) is safe and does not have a detrimental effect on the balance of micronutrients in the body.

Toxaprevent can be used in various ways to help with various conditions. As such, the length of time for using Toxaprevent and the manner in which Toxaprevent is used can vary. For more information on how to use Toxaprevent for different conditions, please click here to download the Clinical Considerations booklet. This can also be found in the Downloads section of your practitioner account. You can also call us on 02476 363873 or e-mail us on with any questions you might have.

We value practitioners. A lot. And we want to give you best service we can possibly provide. On top of the benefits of having a practitioner account with us, we provide you with free training across all our products and are there for you if you need us. So, feel free to call us or e-mail us with any questions you might have, or even if it’s just for a chat, and we’ll be happy to help! Practitioner account benefits: Access to practitioner only content and products 35% practitioner discount Access to protocols Choose from 3 client referral codes to give your clients a discount while you earn commission for recommending our products through our website Free product training Special offers for practitioners We look forward to working with you to help you give your clients a better patient outcome and a better quality of life!

Toxaprevent FAQs

No. Other zeolite products are not as safe or as effective as MANC® particles are for the following reasons:

  • MANC® particles are the cleanest form of zeolite, meaning it will not poison your body with anything it has already absorbed. MANC® particles are deeply cleansed of any toxins they may have absorbed before being mined from the ground.
  • MANC® particles are derived from clinoptilolite zeolite, the most effective form of zeolite for its ability to strongly bind with various toxic substances
  • MANC® particles stay in the gut and are not absorbed through the intestinal barrier into the body, meaning the body doesn’t have to metabolise MANC® particles through the liver and kidneys. Instead, MANC® particles are flushed from the body via natural bowel movements, taking the toxic substances they have bound to along with them
  • MANC® particles are vacuum sealed in their packaging so they don’t absorb any toxins in the air before you consume them
  • MANC® particles are classified as medical devices, meaning they don’t interfere with the body’s processes and the scientific evidence that supports its use has been evaluated by an independent body (TUV Rheinland)
  • MANC® particles have been thoroughly tested and come in preparations which ensure they aren’t broken down in stomach acid and can’t release aluminium into the body, unlike other zeolite product (see It is known that clinoptilolite zeolite breaks down in acid and releases aluminium. Does this mean MANC® particles could poison me with aluminium?)
  • MANC® particles only take out toxic substances and leave essential minerals and micronutrients untouched in the body
  • Froximun AG, the manufacturers of MANC® particles, are obliged to have a dedicated responsible person as part of their quality control system who, in the unlikely case that someone has an adverse reaction to MANC® particles, can be contacted to record the adverse event and seek further advice from their expert medical service.

Due to a lack of empirical evidence on the use of Toxaprevent in children under the age of 12 years old, Toxaprevent must only be used on those over 12 years old.

Due to lack of sufficient studies on pregnant mothers, we do not advise patients who are pregnant to take the Toxaprevent digestive range.

No. MANC® particles will not break down in stomach acid and will not poison you.

To ensure your safety as a user, MANC® particles and the Toxaprevent medical devices developed from them went through all product tests and analyses to assess safety and biocompatibility (even before the products were brought onto the market as certified medical devices)

Above all, the possible exposure to aluminium was investigated, since the MANC® particle is an alumino-silicate. Lead was also examined because it is an endogenous trace component found in clinoptilolite.

These tests go through several stages before the products are released, processed and placed on the market.

A comprehensive evaluation of data from clinical studies, and in vitro and in vivo investigations with the raw materials and products showed that the products based on MANC® particles are safe.

The form of the products has been tested by various test bodies, independent doctors, biochemists and medical assessors in the form of biocompatibility tests in accordance with the EN ISO 10993 series and this was confirmed again in 2019.

Toxicity tests:

• Testing the cytotoxicity according to EN ISO 10993-5: 2009 (GLP mode). Result: not cell-toxic, does not lead to any biological-toxicological damage to the test cells

• Tests for systemic toxicity (acute) according to EN ISO 10993-11: 2009. Result: no systemic toxicity.


• Studies showed that the endogenous aluminum and lead components are not removed and therefore not absorbed through the intestine. This has been demonstrated by absorption tests under clinical observation on the human body.

• Clinical studies showed that clinical chemistry and hematology, and mineral status of users did not change.

Further pre clinical research showed that clinoptilolite:

• can bind heavy metals such as lead in vitro in a simulated gastrointestinal environment

• caused a decrease in aluminum concentrations in the plasma, liver and bones of animals poisoned with aluminum

• in the mouse model, can reduce cytotoxicity caused by lead and the lead concentration in the organism decreased.

Other quality features to completely rule out unlikely residual risks:

• Use of gastro-resistant capsules (Medi PURE and Medi ACUTE), which consists of harmless fiber (HPMC, gellan). This avoids the interaction of MANC® particles with gastric acid, which completely prevents the removal of trace elements in an acidic environment.

• The second measure is to add pH-increasing additives, such as calcium carbonate and magnesium carbonate, to the MANC® particles in Medi PLUS Sachets, allowing for passage through the gastric acid without the need for enteric-coated capsules. The same applies to the admixtures of HALISTOP® Chewable Tablets.

The structure of clinoptilolite zeolite is made from aluminium and silica and it is known that this structure breaks down and releases aluminium in stomach acid. All products containing clinoptilolite must therefore be specifically formulated and prepared to ensure aluminium is not released from the structure of clinoptilolite particles.

Unlike other clinoptilolite products, MANC® particles will not break down and will not release aluminium into the body

Toxaprevent PLUS Sachets have added magnesium carbonate and calcium carbonate to increase the pH level of stomach, thereby reducing the acidity in the stomach. This ensures that the stomach acid is not acidic enough to break MANC® particles, and allows them to reach the intestinal tract safely and intact. The pH level in the intestinal tract is too high to break the particle down so aluminium will not be released from the particle. Similarly, the HALISTOP® Chewable Tablets contain ad-mixtures which increase the pH of the stomach to allow for the safe passage of MANC® particles into the intestinal tract without poisoning the body with aluminium.

MANC® particles in capsule form (PURE and ACUTE Capsules) completely by-pass the stomach acid due to the gastro-resistant capsules used. The capsules allow MANC® particles to completely avoid acid in the stomach and only open in the intestinal tract where the acidity level is too high to break MANC® particles down.

In vivo and in vitro studies have proved this. The aluminium levels in long-term users of products containing MANC® particles (Toxaprevent) as well as the aluminium content of the MANC® particles were checked. Patients were given MANC® particles in their various forms. Stool samples were collected and analysed, and showed that the aluminium content of MANC® was higher after it had been excreted, meaning that MANC® particles were in fact binding and removing aluminium from the body, and was not poisoning the body with aluminium. All patients reported undetectable levels of aluminium after using MANC® particles for various periods of time. MANC® is completely safe to use with no risk of aluminium poisoning.

As such, any products containing clinoptilolite must meet the rigorous high standards which MANC® particles meet in order to be considered safe for human consumption and to avoid poisoning with aluminium from clinoptilolite. This is just one of the many reasons why MANC® particles are the safest form of clinoptilolite zeolite available today.

No. Toxaprevent does not interfere with other supplements as MANC® particles have no affinity towards food supplements. If you are worried about this however, you can leave a two hour gap between taking your supplements and Toxaprevent. 

The leaky gut protocol ensures that MANC® particles reach the small intestine uncovered by proteins from food and without binding to any substances in the food. This means that MANC® particles are as ‘empty’ as possible and can exert their maximum effect to bind to histamine in the wall of the small intestine. This reduces inflammation in the gut lining and allows the epithelial tight junctions to repair themselves, strengthening the integrity of gut barrier and allowing it to function as it should.

MANC® particles have been clinically proven to bring markers of intestinal permeability back into the normal physiological range, indicating a reduction in the ‘leakiness’ of the gut. The randomized, double-blinded, placebo-controlled trial was done on 52 endurance trained men and women over 12 weeks. 

The addition of colostrum in the ACUTE Capsules help rebalance the immune system which can become overactive. An overactive immune system can result from a leaky gut that allows substances that shouldn’t be entering the body to pass through the intestinal barrier. This results in auto-immune conditions such as ulcerative colitis and Hashimoto’s thyroiditis as the immune system starts attacking the body’s own tissues. 

The ACUTE Capsules present a two-pronged attack against leaky gut syndrome; i) fix the leaky gut with MANC® particles and ii) rebalance the immune system with colostrum.

The active ingredient in Toxaprevent is called MANC® (Modified and Activated Natural Clinoptilolite). MANC® particles are negatively charged and work like magnetic ‘sponge’. It emits a negative charge that allows it to naturally absorbs the toxic substances histamine, ammonium and heavy metals (lead and mercury), as well as other bio-genic amines. These toxins can be absorbed inside the ‘cage-like’ structure of MANC® and adsorbed on the surface of the MANC® particle.

MANC® particles are optimised in size and only particles between 6 and 10 microns are selected for Toxaprevent (one micron is one thousandth of a millimetre). At this size, MANC® particles are too large to be absorbed through the intestinal barrier into the bloodstream, and are too small to bind to micronutrients. The result is that MANC® particles stay within the digestive tract only, where they selectively bind to only toxic substances. MANC® particles and the toxic substances they have bound are then removed from the digestive tract via natural bowel movements. This means your body doesn’t have to break down and process MANC® particles or any toxins the MANC® particles have bound to.

The Toxaprevent SKIN range also uses MANC® particles as the active ingredient. MANC® particles are not absorbed through the skin and do not enter the body due to the size of MANC® particles. MANC® particles bind toxins on the skin and prevent them from entering the body through the skin. In particular, histamine can be bound and eliminated from skin, helping to prevent and reduce inflamed skin.

The Toxaprevent SKIN range has three different products – Powder, Salve and Suspension – that target the skin in different ways. To find out which product is right for you go to “Which Toxaprevent product is right for me?” in FAQ’s

Toxaprevent is designed for daily use and can be taken on a continuous basis. Reports have shown that long term use (10+ years) is safe and does not have a detrimental effect on the balance of micronutrients in the body. For condition-specific protocols please speak with your healthcare practitioner. 

The body is constantly detoxifying itself through the liver, kidneys and skin. The metabolic organs are often constantly overburdened with toxins, working at full capacity, and still don’t have the capacity to eliminate toxins effectively on a daily basis. Toxaprevent should be used on a continuous basis to help with the daily cleansing and elimination of these harmful substances from the body. This will help to prevent a build-up of these toxins in the body, reducing their ability to contribute towards adverse health conditions such as inflammation and autoimmune conditions, among many others.

In addition, the minimum duration of use for Toxaprevent may depend on the condition being targeted. You can refer to our conditions to learn more

There are many ways to know whether or not Toxaprevent is working because it has a wide range of applications due to the way it works and the benefits can vary from one person to another. Toxaprevent can benefit you in a variety of ways such as binding to toxins to help strengthen the intestinal barrier especially during intestinal permeability which are linked to many health conditions.

Toxaprevent also relieves the liver and kidneys by reducing the daily toxic burden they must deal with. Removing the toxins before they are transported by the portal vein into the liver and kidneys to be processed gives the metabolic organs an enormous capacity to remove the stored toxins safely. As a result, the body is more responsive to medical treatments and natural remedies and overall has more energy. 

Toxaprevent is scientifically backed, so even if any of these effects aren’t felt, rest assured that Toxaprevent is still absorbing poisonous toxins which are continuously created by the body, e.g. ammonium.

Ammonium can be produced in the digestive tract through several mechanisms. One of the most common ways is through bacteria which produce the urease enzyme. The urease enzyme has the ability to break down urea, a substance which is present in throughout the digestive tract, and splits urea into carbon dioxide and ammonia (ammonia is the non-ionic form of ammonium). In order for ammonia to be converted into ammonium, it needs an extra hydrogen atom which it can gain from acid e.g. stomach acid. 

H. pylori, for example, affects an estimated 50% of the population and is a bacterial infestation of the stomach which creates the urease enzyme to convert urea into carbon dioxide and ammonia. The ammonia is then used as a ‘shield’ to protect itself from being killed by stomach acid as it neutralise stomach acid. When this happens, the stomach acid donates a hydrogen atom to ammonia and turns ammonia into ammonium, a positively charged ion which MANC® particles can bind to.

Lower down in the intestinal tract, bacteria such as also produce the urease enzyme, releasing ammonia from urea in the colon. Simultaneously, certain anaerobic bacteria such as bacteroides, bifidobacterium, aspergillus, ruminococcus, peptostreptococcus, fusobacterium, lactobacillus, streptococcus play a role in fermenting dietary fibres to create short chain fatty acids such as acetate, propionate, and butyrate, which contain the hydrogen atom. This provides the necessary conditions for protonation to occur whereby ammonia takes up a hydrogen atom from the short chain fatty acids and converts into ammonium. This process is known as protonation.

MANC® particles are derived from correctly processing clinoptilolite zeolite to ensure they are safe enough eliminate heavy metals, histamine and ammonium from the body safely. In order for clinoptilolite zeolite to be safe for human consumption it must cleansed of any and all toxins it has already absorbed (from the ground it was taken from) and it must stay only in the digestive tract. MANC® particles are produced once the clinoptilolite zeolite has been cleansed and the size of the particles are between 6 – 10 microns – this is how MANC® particles are produced.

Froximun AG are the only company in the world which produces MANC® particles, the gold standard of zeolite.

Zeolites particles are natural, mineral based substances formed when volcanic ash crystalizes with salt water. Volcanic zeolites are probably one of the oldest and most versatile active ingredients used by humans. They emit a negative charge which allows them to work like a ‘magnetic sponge’ so they can absorb positively charged toxic substances including histamine, ammonium and heavy metals (lead and mercury), all of which can contribute to ill health. These toxins can be stored in ‘cages’ which run through the zeolite particles.

There are many different zeolites which have their own qualities, structures and compositions. Clinoptilolite zeolite has been shown to be the most effective form of zeolite, meaning it out-performs all other types of zeolite when binding toxic substances. This is why MANC® particles are made from only the highest quality clinoptilolite zeolite.

All Toxaprevent products are based on the active ingredient MANC®, the cleanest, safest and most effective zeolite available.

For children 12 – 16 years old take half the recommended dosage and drink plenty of fluids throughout the day to ensure Toxaprevent transits gently through the digestive tract without causing constipation.

Each of the products in the Toxaprevent range have been carefully designed to target specific areas of the digestive tract and specific conditions of the skin. To find out which product is right for you go to “Which Toxaprevent product is right for me?” in FAQ’s.

Each of the products in the Toxaprevent range have been carefully designed to target specific areas of the digestive tract and specific skin conditions. All Toxaprevent products use MANC® particles as the main active ingredient to bind and eliminate histamine, ammonium and heavy metals from different parts of the body. Below is a quick overview of where each of the Toxaprevent products work in the body.

For a full breakdown of which Toxaprevent product is best for you, please read below, or you can view a specific condition page which recommends a protocol to combat that condition If in doubt please get in touch and we can schedule a health call.

Toxaprevent Dentura Med Toothpaste

Toxaprevent Dentura Med can be used like as a regular toothpaste in the morning and at night. The toothpaste contains MANC® particles alongside a combination of natural ingredients with no fluoride.

Toxaprevent HALISTOP Chewable Tablets

HALISTOP Chewable Tablets are targeted towards the mouth and throat. The tablets can be chewed thoroughly before swallowing or can be left in the mouth like a lozenge. This concentrates MANC® particles in the mouth and throat, where they can help with inflammation and wound healing in the gums, and bind to ammonium and sulphur compounds which contribute to bad breath (halitosis). 

Toxaprevent Medi PLUS Sachets

The Medi PLUS Sachets must be added to water and drank. This will allow MANC® particles contained in the sachets to primarily target the upper digestive tract (mouth, oesophagus and stomach). The PLUS Sachets will still work in the lower digestive tract (small intestine and colon), however their ability to uptake harmful substances in the lower digestive tract will be slightly reduced because MANC® particles will have already taken up harmful substances from the upper digestive tract.

Toxaprevent Medi PURE Capsules

The Medi PURE Capsules are gastro-resistant which means they will not break down in the stomach’s acidic environment. This allows them to by-pass the stomach and reach the small intestinal tract. Thanks to the gastro-resistant capsules, MANC® particles will be released directly into the lower digestive tract so they can target the small intestine and colon.

Toxaprevent Medi ACUTE Capsules

The Medi ACUTE Capsules are gastro-resistant which means they will not break down in the stomach’s acidic environment. This allows them to by-pass the stomach and reach the small intestinal tract. Thanks to the gastro-resistant capsules, MANC® particles and colostrum will be released directly into the lower digestive tract so they can target the small intestine and colon.

Toxaprevent SKIN Powder

The SKIN Powder is applied directly onto the surface of skin and in open wounds. This is particularly useful for binding histamine immediately after bug bites or stings, and to accelerate healing in wounds such as skin ulcers. MANC® particles bind histamine and heavy metals which slow down primary haemostasis in wounds, and also triggers the blood clotting cascade via the release of calcium into the wound.

Toxaprevent SKIN Salve

The SKIN Salve is applied directly onto the surface of skin where it binds histamine. This reduces inflammation on the surface of the skin. 

Toxaprevent SKIN Suspension

The SKIN Suspension uses colloidal water to penetrate the skin, allowing MANC® particles to bind histamine underneath the surface of the skin. This is useful in cases of more severe dermatitis.

What is the difference between the Medi PLUS Sachets, Medi PURE Capsules and Medi ACUTE Capsules?

The Medi PLUS Sachets release MANC® particles in the upper digestive tract, whereas Medi PURE Capsules and Medi ACUTE Capsules both release MANC® particles in the lower digestive tract. 

Therefore, you can choose which area of the digestive tract you want to remove harmful substances from by choosing the appropriate product.

MANC® particles do not have a physiological, pharmacological or immunological effect on the body. They are inert and work by using a physical mechanism (ion exchange) to safely bind toxic substances whist travelling through the digestive tract and are eventually passed out of the body through natural bowel movements. As such, MANC® particles do not interfere with the body’s physiological processes, nor is it absorbed by the body, and this is the main reason as to why it has been successfully registered as a medical device.

For safety and effectiveness, all clinoptilolite zeolite products, including MANC® particles, need to be vacuum sealed in air tight sachets or capsules. 

Clinoptilolite zeolite will immediately bind to toxins in the air as soon as they opened from their packaging and exposed to the air, causing contamination. Each time clinoptilolite zeolite is exposed to the air presents another opportunity for clinoptilolite zeolite to bind to more toxins. These toxins take up some of the ‘cages’ in clinoptilolite (reducing its ability to uptake harmful substances in the body) and may poison the body upon consumption of clinoptilolite zeolite – defeating the purpose of taking clinoptilolite in the first place i.e. to detoxify the body of harmful substances and not add to it. This means that clinoptilolite zeolite products which are not vacuum sealed may not be safe for human consumption because the unwanted toxins they absorb from the air could begin to poison the body and reduce their effectiveness. 

Each dose of MANC® particles is packaged in vacuum sealed sachets and blister packs to ensure that the time allowed for contamination with toxins in the air is absolutely minimal. This allows you to open one full dose immediately before you need to take it and consume right away without having to open and store the rest of the MANC® particles – instead of having to scoop it out of a tub and then reseal. This means MANC® particles keep their safety and efficacy.

Magnesium carbonate and calcium carbonate are added to increase the pH level in the stomach (to reduce the acidity). This allows MANC® particles to safely pass through to the small intestine without being broken down by stomach acid. 

Magnesium carbonate and calcium carbonate have also been found to bind to oxalates.

Froximun AG, the manufacturers of Toxaprevent, are obliged to have a dedicated responsible person as part of their quality control system who, in the unlikely case that an individual has an adverse reaction to MANC® particles, can be contacted to record the adverse event and seek further advice from their expert medical service. This is put in place as a measure for the safety and protection of those taking Toxaprevent.  

Food supplements containing clinoptilolite zeolite do not have a responsible person who can be contacted in the case of adverse reactions. See ‘Are other zeolites as safe and as effective as MANC® particles? for more information on what makes a zeolite product safe for human consumption.

Ammonium is a natural by-product of protein digestion, which is broken down by the liver and expelled from the body via the kidneys. Maintaining a low level of ammonium is important as it helps to reduce the toxic burden on the liver, thereby helping to optimise liver function.

Ammonium is a toxic substance when it exists in excess amounts in the body. Low levels of ammonium are healthy as this contributes to balancing the body’s natural pH level, however high levels of ammonium can become toxic to the body.

High levels of ammonium production can contribute to poor health as the liver and kidneys will need to work harder to clear excess ammonium from the body. In cases where the liver is already overburdened and functioning poorly, the liver may be unable to effectively detoxify ammonium, causing an excess amount of ammonium. Excess ammonium can become toxic to the brain and nervous system, and can contribute to a feeling of lethargy, being unwell and brain fog, as well as further diminishing the functionality of the liver and kidneys. High levels of ammonium in the body can also be a contributing factor to dementia and other mental illnesses.

Many of the illnesses caused by high ammonium levels in the body are chronic and untreatable, so the safest course of action is to protect your liver and kidneys to avoid damage to them. 

In addition, the liver will take the important substance bicarbonate, which is produced to counteract stomach acid, from the stomach through the portal vein and uses it to detoxify ammonium in the liver. High ammonium levels mean more bicarbonate is taken which leaves less bicarbonate to counteract stomach acid in the stomach. This can result in high levels of stomach acid and acid reflux symptoms.

Regular use with Toxaprevent will bind and remove excess ammonium from the digestive tract, meaning the liver and kidneys will not have to bear the burden of any ammonium carried out of the system with MANC® particles.

In vivo studies on MANC® have shown that particles over 6 microns (one micron is one thousandth of a millimetre) are not absorbed by the body and therefore cannot further burden the liver and kidneys. This is important as zeolite particles below 6 microns size may enter the body, which could cause severe detox reactions as well as placing a further burden on the liver and kidneys. Given that these metabolic organs are usually already over-burdened, if small zeolite particles under 6 microns were to enter the system and bind to stored toxins (stored in fat, muscle or bone, etc.), these zeolite particles would eventually need to be removed from the body via the liver and kidney, at which point those toxins could potentially be deposited into the liver and kidney. Therefore, the liver and kidneys will need to eliminate not only the small zeolite particles, but also the toxins it will carry.

MANC® particles are also limited to a maximum particle size of 10 microns. This ensures essential minerals and micronutrients are not bound by MANC® particles. Zeolite particles above 10 microns can bind to essential minerals and micronutrients and can deplete them from the body. 

This is why optimising MANC® particles between 6-10 microns is vital. The result is that MANC® particles selectively bind to only toxic substances in the body, and actually reduces the toxic burden on the liver and kidneys, making MANC® the safest zeolite to use.

Even with a perfectly tailored diet that delivers the right nutrients at the optimal doses, the human body is continuously overburdened with environmental toxins as well as those created inside the body. In particular, heavy metals, ammonium and excess histamine can lead to many health conditions if left unchecked. These substances can be extremely difficult to eliminate from the body and will exacerbate existing health conditions, making it difficult to achieve optimal health and wellbeing.

Toxaprevent is an ideal solution to eliminate heavy metals, ammonium and histamine from the body using MANC® particles. MANC® particles are the safest and most effective way to naturally chelate and detoxify the body. MANC® particles represent the gold standard in the chelation of heavy metals and the elimination of histamine and ammonium from the body as it safely binds these in the digestive tract. MANC® particles are too large to be absorbed by the body through the gut barrier, meaning any harmful substances the bind will be removed from the body alongside MANC® particles via natural bowel movements.

MANC® particles enable you, as a practitioner, to provide your clients with a solid foundation upon which to build your chosen therapies and protocols. By stripping away harmful substances, fixing a leaky gut and relieving the liver of its toxic burden, any supplementation and diet regime you recommend to your clients will have a significantly higher chance of success.

Due to the way MANC® particles works and the various preparations in which they are available, Toxaprevent has many areas of applications such as leaky gut, autoimmune conditions, liver and kidney relief, and much more. For protocols on how Toxaprevent works on various conditions, please see our dedication pages on specific conditions.

Clinoptilolite zeolite particles should never be absorbed into the body. The body usually deals with particles taken in through the mouth (usually particles carried in with food) by keeping them in the intestinal tract where they are unable to cross the intestinal barrier into the body. Particles are then eliminated via natural bowel movements. Although smaller particles (those under 3 microns and including nano sized particles) of clinoptilolite are more favourable (because they have a larger surface area which allows them to absorb more toxic substances than larger particles), these are too small as they can be absorbed through the intestinal barrier and into the body. The liver and kidneys will then be tasked with the job of removing them from the body which will be difficult because the body doesn’t have a detoxification pathway for particles once they are absorbed into the body. Transporting these small clinoptilolite particles around the body could potentially lead to ‘clogging up’ of particles in various parts of the body such as the kidneys or gall bladder, and can further contribute to ill health and a feeling of being unwell.

Our metabolic organs are usually already over-worked and over-burdened with daily toxins from the food we eat, pollution, and toxic substances created within the body – any small clinoptilolite particles will only add to the workload. It is therefore important that clinoptilolite particles stay within the digestive tract and are not absorbed by the body. MANC® particles achieve this by ensuring that the particle size is small enough to bind as many toxic substances as possible (for maximum effectiveness) whilst being too large to pass through the intestinal barrier. In other words, MANC® particles are optimal in size.

Although smaller clinoptilolite particles may bind toxins that are stored in the body (in fats, muscles, etc.), getting them back out of the body is difficult, and potentially dangerous! This is why MANC® particles only stay in the digestive tract – because this is the only part of the body that is adequately equipped to eliminate particles. As a result, toxins bound by MANC® particles in the digestive tract are removed via bowel movements, instead of being absorbed. This means that the liver and kidneys are relieved of their daily toxic burden and can function more effectively to handle daily toxins. 

No. Toxaprevent will not bind to micronutrients and essential minerals due to the following reasons:

  • MANC® particles have a maximum size of 10 microns which is too small to bind to many nutrients which are larger in size
  • MANC® particles exhibit a negative charge which attract positively charged ions through a process known as ion exchange. This gives them an affinity to bind to toxins which have a high positive charge
  • MANC® particles are preloaded with minerals (potassium, calcium, sodium, magnesium) which are deposited into the body in return for more toxic, highly charged substances such as heavy metals.

MANC® particles therefore selectively bind with toxic substances and leave micronutrients and essential minerals untouched in the body.

Reports and studies generated by the manufacturer of Toxaprevent, Froximun AG, showed that long term use of Toxaprevent did not deplete levels of micronutrients and essential minerals in patients. Toxaprevent can therefore be taken alongside food, and other supplements and minerals.

Toxaprevent has no direct side effects because it is not absorbed by the body and does not interfere with the body’s physiological processes. 

MANC® particles contained in Toxaprevent work autonomously simply bind harmful toxins in the digestive tract, move through the digestive tract and are then passed out via natural bowel movements. (Please see absorption study for further information).

Please leave two hours between taking medications and the Toxaprevent Digestive range (PLUS/PURE/ACUTE/HALISTOP). Due to the high absorption capacity of MANC® particles, it is possible that Toxaprevent may bind to medications and take them out of the body too. Therefore, a two hour gap is needed between taking medications and Toxaprevent to ensure that the absorption of medications into the body is not disturbed.

After applying medicated creams, salves, etc., wait at least 60 minutes before applying products in the Toxaprevent SKIN range (Suspension/Salve/Powder). 

In cases of doubt, consult your doctor or health practitioner about using Toxaprevent together with other medications.



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