Lactobacillus Reuteri DSM17648 – an alternative in the first-line of helicobacter pylori eradication

The present study included 70 patients diagnosed with Helicobacter pylori infection by the rapid urease test, randomized into two therapeutic regimens: Lactobacillus reuteri DSMZ17648, liquorice and calcium carbonate and classical proton pump inhibitor – amoxicillin – clarithromycin scheme. The eradication efficiency was 54.3% in the Lactobacillus reuteri group vs 77.1% in the antibiotic group (p = 0.042) but with a significantly lower rate of side effects (2.9% vs 17.1%, p = 0.037). Finding new drugs to eradicate Helicobacter pylori with increased efficacy, cost effectiveness ratio and no side effects remains a challenge.

Keywords: Helicobacter pylori, eradication, antibiotic resistance, Lactobacillus reuteri

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