SIBO is the presence of an excessive number of bacteria in the small intestine. The small intestine extends from the pyloric sphincter of the stomach and empties into the large intestine (colon). Its function is completion of the digestive process, absorption of nutrients into the bloodstream and passing on the residue to the colon.
Unlike the colon which is home to a lot of different kinds of bacteria, the small colon is relatively sterile and has very few bacteria. This is due to the presence of bile and the fast flow of food through it. The sterile environment and low number of bacteria is maintained by several processes and mechanisms. Any compromise of this can lead to an increase in bacterial growth.
Structural abnormalities of the gastrointestinal tract (GI tract) as a result of surgery, medication or illnesses such as Crohn’s can cause obstructions and affect the fast and effective movement of food along it. This slower movement of food causes stagnation and creates a breeding ground for bacteria. Similarly, any motility disorders of the small intestine can have a similar effect. The growing bacteria will produce toxins which further favour the breeding environment allowing even more growth. This stagnation of food, growth of bacteria and resulting inflammation also affects the effective absorption of nutrients into the bloodstream.
A reduction in the production of gastric acid can also lead to SIBO. Optimum gastric acid is essential for the effective digestion of food in the stomach so that what is passed into the small intestine is ready for the final digestive process and absorption. The gastric acid ensures that any pathogens are killed and any growth of bacteria in the food is supressed before it is passed down. Reduced acid production, as a result of H. pylori infections for example, means this mechanism isn’t as effective, thereby being another cause of SIBO. Reduced acid production can also be as a result of medication such as PPI’s, as used for Acid Reflux.
People who are immunodeficient are also prone to SIBO. Once SIBO is present it can cause inflammation of the intestinal mucosa which further exacerbates the symptoms and can affect intestinal mucosal immunity.
SIBO affects far more people than originally thought but the symptoms are often diagnosed as other issues. Symptoms associated with SIBO include abdominal pain, distension, bloating, diarrhoea, flatulence and weakness. As the symptoms for IBS are very similar, it can often be linked. SIBO is often the cause of chronic diarrhoea, malabsorption, nutritional deficiency, unintentional weight loss and osteoporosis.
Toxaprevent binds to and eliminates the toxins from the intestine, thereby making the environment less favourable for the bacteria to grow and spread. Removing histamine from the intestines helps relieve inflammation of the intestinal wall and strengthens it. This in turn helps with the motility and absorption of nutrients.
Toxaprevent Medi PURE Capsules are designed to target the lower digestive tract, to bind to and remove toxins from the intestines.
Toxaprevent Medi PLUS Sachets are designed to target the upper digestive tract and is used to help with H. pylori and Acid reflux which will in turn help with SIBO by allowing the body to return to its normal mechanism of acid production.